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Why gene-edited crops should be subject to the same strict rules and regulations as GM crops, promoted by MNCs

By Bharat Dogra
 
As consciousness regarding the many-sided adverse impacts and high hazards and risks of GM crops have grown, some promoters allied to the same big business interests and multinational companies directly and indirectly have instead started trying to push for gene editing technologies but as these too have similar adverse impacts and risks to a large extent therefore these too must be rejected. This is supported by scientific research as well as court decisions. 
In a study published in Nature Biotechnology, scientists from the Wellcome Sanger Institute in the UK found that new genetic engineering techniques like CRISPR may cause ‘genetic havoc’. Researchers found large deletions and rearrangements of DNA near the target site that were not intended. Earlier studies also found that gene-edited plants such as soybeans had off-target effects in which gene-editing occurred at unintended locations. Friends of the Earth found on the basis of the actual applications of these techniques that this was in the direction of further increasing chemical intensive approach to agriculture. 
Gene editing can also be used to construct ‘gene drives’ which aim to spread genetically modified genes across wild populations faster than normal inheritance allows. Once released, gene drive organisms cannot be recalled. This can have very adverse impacts and there have been several demands for moratorium on this. Use of this technology on mosquitoes and insects has proved very controversial and there have been several adverse impacts and high risks reported regarding this.        
     In fact the entire trend and tendency of big business interests and multinational companies gaining control over seeds and agriculture must be firmly opposed by farmers, health and environment activists all over the world because big business operates in ways that are harmful for sustainable livelihoods of small farmers, for environment and health. On the one hand they try to spread inherently unstable, unreliable, disruptive and dangerous technologies like GM and gene-editing and on the other also market herbicides and agro-chemicals that are expensive as well as harmful for health and environment.
One of the the most eminent scientist of India on this subject Dr. Pushpa Bhargava has clearly stated that the available evidence is overwhelmingly GM crops. Dr. Pushpa M. Bhargava was the founder of the Centre for Cellular and Molecular Biology and in addition he was also the Vice Chairperson of the National Knowledge Commission. Many people’s science movements looked upon him as their mentor. He had been appointed by the Supreme Court of India as an observer in the Genetic Engineering Appraisal Committee as he was widely perceived to be not only a very accomplished expert on this issue and that too of the highest integrity but in addition he was also seen on the basis of his past record as a very strong and persistent defender of public interest.
Therefore it is very useful and interesting to see what this very senior scientist with a comprehensive understanding of this issue had to say about GM crops in an article written for a leading newspaper The Hindustan Times.  He wrote, “There are over 500 research publications by scientists of indisputable integrity, who have no conflict of interest, that establish harmful effects of GM crops on human, animal and plant health, and on the environment and biodiversity. For example, a recent paper by Indian scientists showed that the Bt gene in both cotton and brinjal leads to inhibition of growth and development of the plant. On the other hand, virtually every paper supporting GM crops is by scientists who have a declared conflict of interest or whose credibility and integrity can be doubted.”
In addition, in a review of recent trends titled 'Food Without Choice' (published in another leading newspaper The Tribune) Prof. Pushpa  Bhargava  drew pointed attention to the "attempt by a small but powerful minority to propagate genetically modified  crops to serve their interests and those of multinational corporations  (read the US), the bureaucracy, the political set-up and a few unprincipled and unethical scientists and technologists who can be used as tools." Further he warned, "The ultimate goal of this attempt in India of which the leader is Monsanto, is to obtain control over Indian agriculture and thus food production. With 60 per cent of our population engaged in agriculture and living in villages, this would essentially mean not only a control over our food security but also over our farmer security, agricultural security and security of the rural sector."
The strong stand of Dr. Bhargava against GM crops is supported by other eminent scientists in various parts of world. A group of eminent scientists organized under the Independent Science Panel have stated in very clear terms, "GM crops have failed to deliver the promised benefits and are posing escalating problems on the farm. Transgenic contamination is now widely acknowledged to be unavoidable, and hence there can be no co-existence of GM and non-GM agriculture. Most important of all, GM crops have not been proven safe. On the contrary, sufficient evidence has emerged to raise serious safety concerns, that if ignored could result in irreversible damage to health and the environment. GM crops should be firmly rejected now."
The Independent Science Panel (ISP) is a panel of scientists from many disciplines and countries, committed to the promotion of science for the public good. In a document titled 'The case for a GMO-free Sustainable World' the ISP has stated further, "By far the most insidious dangers of genetic engineering are inherent to the process itself, which greatly enhances the scope and probability of horizontal gene transfer and recombination, the main route to creating viruses and bacteria that cause disease epidemics. This was highlighted, in 2001, by the 'accidental' creation of a killer mouse virus in the course of an apparently innocent genetic engineering experiment. Newer techniques, such as DNA shuffling, are allowing geneticists to create in a matter of minutes in the laboratory millions of recombinant viruses that have never existed in billions of years of evolution. Disease-causing viruses and bacteria and their genetic material are the predominant materials and tools for genetic engineering, as much as for the intentional creation of bio-weapons.”
Several scientists involved in studying the implications and impacts of genetic engineering got together at the International Conference on 'Redefining of Life Sciences' organised at Penang, Malaysia, by the Third World Network. They issued a statement (the Penang Statement, or PS) which questioned the scientific basis of genetic engineering. This statement said, "The new biotechnology based upon genetic engineering makes the assumption that each specific feature of an organism is encoded in one or a few specific, stable genes, so that the transfer of these genes results in the transfer of a discrete feature. This extreme form of genetic reductionism has already been rejected by the majority of biologists and many other members of the intellectual community because it fails to take into account the complex interactions between genes and their cellular, extracellular and external environments that are involved in the development of all traits.
"It has thus been impossible to predict the consequences of transferring a gene from one type of organism to another in a significant number of cases. The limited ability to transfer identifiable molecular characteristics between organisms through genetic engineering does not constitute the demonstration of any comprehensive or reliable system for predicting all the significant effects of transposing genes."
Highest Europe Court Ruling Confirms Serious Risks of Gene-Edited Crops
At a time when more and more people in the world are becoming concerned about the serious health risks and numerous other adverse impacts of genetically modified (GM) crops and genetically modified organisms (GMOs), the enormously powerful  billion dollar GMO multinationals tried again to introduce confusion and uncertainty in public mind by coming up with the concept of gene-edited crops and claiming that these should not be subject to the same restrictions as GM crops. However in July 2018 the highest court in Europe ruled that gene-edited crops should be subject to the same strict rules and regulations as GM crops.
Earlier a review of the legal and scientific facts surrounding this debate by Dr. Janet Cotter and Dr. R. Steinbrecher ( published in the Ecologist) had concluded, “ It is clear that gene-edited crops and animals need to be assumed as GMOs in the same way as current GM crops.” The court verdict is along similar lines.
With gene editing researchers can add, delete or modify bits of an organism’s genome. The European Court said that any crops edited using CRISPR or other gene-editing techniques must abide by the same laws restricting the use of GMOs. More specifically the Court  concluded it “considers that the risks linked to the use of these new mutagenesis techniques might prove to be similar to those that result from production and release of a GMO through trans-genesis, since the direct modification of the genetic material of an organism through mutagenesis makes it possible to obtain the same effects as the introduction of foreign gene into the organism (trans-genesis) and these new techniques make it possible to introduce genetically modified varieties at a rate out of all proportion to those resulting from the application of conventional methods of mutagenesis.”   
Welcoming the court verdict Franziska Achterberg, Greenpeace EU’s food policy director said, “ Releasing these new GMOs into the environment without proper safety measures  is illegal and irresponsible, particularly given that gene editing can lead to unintended side-effects… The European Commission and the European governments must now ensure that all new GMOs are fully tested and labeled, and that any field trials are brought under GMO rules.”
A spokesperson of Friends of the Earth said, “We applaud the European Court of Justice for this forward looking decision.” 
---
The writer is Honorary Convener, Campaign to Save Earth Now. His recent books include India’s Quest for Sustainable Farming and Healthy Food, Man over Machine, Protecting Earth for Children, and A Day in 2071

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